MECHANISM OF ACTION OF METHOTREXATE. IV. FREE INTRACELLULAR METHOTREXATE REQUIRED TO SUPRESS DIHYDROFOLATE REDUCTION TO TETRAHYDROFOLATE BY EHRLICH ASCITES TUMOR CELLS IN VITRO.WHITE JC; GOLDMAN ID.1976; MOLEC. PHARMACOL.; U.S.A.; DA. 1976; VOL. 12; NO 5; PP. 711-719; BIBL. 41 REF.Article

INHIBITION OF THE MEMBRANE TRANSPORT OF FOLATES BY ANIONS RETAINED IN UREMIA = INHIBITION DU TRANSPORT MEMBRANAIRE DES FOLATES PAR LES ANIONS RETENUS DANS L'UREMIEJENNETTE JC; GOLDMAN ID.1975; J. LAB. CLIN. MED.; U.S.A.; DA. 1975; VOL. 86; NO 5; PP. 834-843; BIBL. 19 REF.Article

THE RELATIONSHIP AMONG TRANSPORT, INTRACELLULAR BINDING, AND INHIBITION OF RNA SYNTHESIS BY ACTINOMYCIN D IN EHRLICH ASCITES TUMOR CELLS IN VITRO. = RELATION ENTRE LE TRANSPORT, LA FIXATION INTRACELLULAIRE ET L'INHIBITION DE LA SYNTHESE D'ARN PAR L'ACTINOMYCINE D DANS LES CELLULES DE LA TUMEUR ASCITIQUE D'EHRLICH IN VITROBOWEN D; GOLDMAN ID.1975; CANCER RES.; U.S.A.; DA. 1975; VOL. 35; NO 11; PP. 3054-3060; BIBL. 35 REF.Article

FURTHER STUDIES ON THE CHARGE-RELATED ALTERATIONS OF METHOTREXATE TRANSPORT IN EHRLICH ASCITES TUMOR CELLS BY IONIC LIPOSOMES: CORRELATION WITH LIPOSOME-CELL ASSOCIATIONFRY DW; GOLDMAN ID.1982; J. MEMBR. BIOL.; ISSN 0022-2631; USA; DA. 1982; VOL. 66; NO 2; PP. 87-95; BIBL. 51 REF.Article

METHOTREXATE RESISTANCE IN AN L1210 CELL LINE RESULTING FROM INCREASED DIHYDROFOLATE REDUCTASE, DECREASED THYMIDYLATE SYNTHETASE ACTIVITY, AND NORMAL MEMBRANE TRANSPORT: COMPUTER SIMULATIONS BASED ON NETWORK THERMODYNAMICSWHITE JC; GOLDMAN ID.1981; J. BIOL. CHEM.; ISSN 0021-9258; USA; DA. 1981; VOL. 256; NO 11; PP. 5722-5727; BIBL. 30 REF.Article

EFFLUX IN ISOLATED HEPATOCYTES AS A POSSIBLE CORRELATE OF SECRETION IN VIVO: INDUCED EXIT OF THE FOLIC ACID ANALOG METHOTREXATE, BY DIBUTYRYL CYCLIC AMP OR ISOBUTYL METHYL XANTHINEGEWIRTZ DA; RANDOLPH JK; GOLDMAN ID et al.1981; BIOCHEM. BIOPHYS. RES. COMMUN.; ISSN 0006-291X; USA; DA. 1981; VOL. 101; NO 2; PP. 366-374; BIBL. 32 REF.Article

POTENT BILE SALT AND ORGANIC ANION INHIBITION OF METHOTREXATE UPTAKE AND ACCUMULATION IN THE FRESHLY ISOLATED RAT HEPATOCYTEGEWIRTZ DA; RANDOLPH JK; GOLDMAN ID et al.1980; CANCER RES.; USA; DA. 1980; VOL. 40; NO 6; PP. 1852-1857; BIBL. 43 REF.Article

DISTINGUISHING BETWEEN MEMBRANE TRANSPORT AND INTRACELLULAR METABOLISM OF FLUORODEOXYURIDINE IN EHRLICH ASCITES TUMOR CELLS BY APPLICATION OF KINETIC AND HIGH PERFORMANCE LIQUID CHROMATOGRAPHIC TECHNIQUESBOWEN D; DIASIO RB; GOLDMAN ID et al.1979; J. BIOL. CHEM.; USA; DA. 1979; VOL. 254; NO 12; PP. 5333-5339; BIBL. 21 REF.Article

RAPID SEPARATION OF LOW MOLECULAR WEIGHT SOLUTES FROM LIPOSOMES WITHOUT DILUTIONFRY DW; WHITE JC; GOLDMAN ID et al.1978; ANAL. BIOCHEM.; USA; DA. 1978; VOL. 90; NO 2; PP. 809-815; BIBL. 32 REF.Article

THE MECHANISM OF ACTION OF METHOTREXATE. III. REQUIREMENT OF FREE INTRACELLULAR METHOTREXATE FOR MAXIMAL SUPPRESSION OF (¹⁴C) FORMATE INCORPORATION INTO NUCLEIC ACIDS AND PROTEIN = MECANISME DE L'ACTION DU METHOTREXATE. III. NECESSITE DE METHOTREXATE INTRACELLULAIRE LIBRE POUR LA SUPPRESSION MAXIMALE DE L'INCORPORATION DE FORMATE ¹⁴C DANS LES ACIDES NUCLEIQUES ET LES PROTEINESWHITE JC; LOFTFIELD S; GOLDMAN ID et al.1975; MOLEC. PHARMACOL.; U.S.A.; DA. 1975; VOL. 11; NO 3; PP. 287-297; BIBL. 1P.Article

TENIPOSIDE (VM-26)- AND ETOPOSIDE (VP-16-213)-INDUCED AUGMENTATION OF METHOTREXATE TRANSPORT AND POLYGLUTAMYLATION IN EHRLICH ASCITES TUMOR CELLS IN VITROYALOWICH JC; FRY DW; GOLDMAN ID et al.1982; CANCER RES.; USA; DA. 1982; VOL. 42; NO 9; PP. 3648-3653; BIBL. 36 REF.Article

AUGMENTATION OF THE INTRACELLULAR LEVELS OF POLYGLUTAMYL DERIVATIVES OF METHOTREXATE BY VINCRISTINE AND PROBENECID IN EHRLICH ASCITES TUMOR CELLSFRY DW; YALOWICH JC; GOLDMAN ID et al.1982; CANCER RES.; ISSN 0008-5472; USA; DA. 1982; VOL. 42; NO 7; PP. 2532-2536; BIBL. 25 REF.Article

K⁺-INDUCED ALTERATIONS OF ENERGETICS AND EXCHANGE DIFFUSION IN THE CARRIER-MEDIATED TRANSPORT OF THE FOLIC ACID ANALOG METHOTREXATE IN EHRLICH ASCITES TUMOR CELLSFRY DW; CYBULSKI RL; GOLDMAN ID et al.1980; BIOCHIM. BIOPHYS. ACTA; ISSN 0006-3002; NLD; DA. 1980; VOL. 603; NO 1; PP. 157-170; BIBL. 33 REF.Article

A REDUCTION IN ENERGY-DEPENDENT AMINO ACID TRANSPORT BY MICROTUBULAR INHIBITORS IN EHRLICH ASCITES TUMOR CELLS.FYFE MJ; LOFTFIELD S; GOLDMAN ID et al.1975; J. CELL. PHYSIOL.; G.B.; DA. 1975; VOL. 86; NO 2; PP. 201-212; BIBL. 1 P.Article

ADENOSINE STIMULATION OF UPHILL ADENINE TRANSPORT IN L1210 LEUKEMIA CELLS: EVIDENCE FOR A NOVEL COUNTERTRANSPORT MECHANISMCYBULSKI RL; FRY DW; GOLDMAN ID et al.1981; J. BIOL. CHEM.; ISSN 0021-9258; USA; DA. 1981; VOL. 256; NO 9; PP. 4455-4459; BIBL. 27 REF.Article

ALTERATIONS OF THE CARRIER-MEDIATED TRANSPORT OF AN ANIONIC SOLUTE, METHOTREXATE, BY CHARGED LIPOSOMES IN EHRLICH ASCITES TUMOR CELLSFRY DW; WHITE JC; GOLDMAN ID et al.1979; J. MEMBRANE BIOL.; USA; DA. 1979; VOL. 50; NO 2; PP. 123-140; BIBL. 49 REF.Article

A BASIS FOR FLUOROPYRIMIDINE-INDUCED ANTAGONISM TO METHOTREXATE IN EHRLICH ASCITES TUMOR CELLS IN VITRO.BOWEN D; WHITE JC; GOLDMAN ID et al.1978; CANCER RES.; U.S.A.; DA. 1978; VOL. 38; NO 1; PP. 219-222; BIBL. 31 REF.Article

RAPID FORMATION OF POLY-GAMMA -GLUTAMYL DERIVATIVES OF METHOTREXATE AND THEIR ASSOCIATION WITH DIHYDROFOLATE REDUCTASE AS ASSESSED BY HIGH PRESSURE LIQUID CHROMATOGRAPHY IN THE EHRLICH ASCITES TUMOR CELL IN VITROFRY DW; YALOWICH JC; GOLDMAN ID et al.1982; J. BIOL. CHEM.; ISSN 0021-9258; USA; DA. 1982; VOL. 257; NO 4; PP. 1890-1896; BIBL. 31 REF.Article

EFFECTS OF 2,4-DINITROPHENOL AND OTHER METABOLIC INHIBITORS ON THE BIDIRECTIONAL CARRIER FLUXES, NET TRANSPORT AND INTRACELLULAR BINDING OF METHOTREXATE IN EHRLICH ASCITES TUMOR CELLSFRY DW; WHITE JC; GOLDMAN ID et al.1980; CANCER RES.; ISSN 0008-5472; USA; DA. 1980; VOL. 40; NO 10; PP. 3669-3673; BIBL. 25 REF.Article

LACK OF STEREOSPECIFICITY AT CARBON 6 OF METHYLTETRAHYDROFOLATE TRANSPORT OF EHRLICH ASCITES TUMOR CELLS. CARRIER-MEDIATED TRANSPORT OF BOTH STEREOISOMERS.WHITE JC; BAILEY BD; GOLDMAN ID et al.1978; J. BIOL. CHEM.; U.S.A.; DA. 1978; VOL. 253; NO 1; PP. 242-245; BIBL. 29 REF.Article

ANALYSIS OF THE ROLE OF MEMBRANE TRANSPORT AND POLYGLUTAMATION OF METHOTREXATE IN GUT AND THE EHRLICH TUMOR IN VIVO AS FACTORS IN DRUG SENSITIVITY AND SELECTIVITY = ANALYSE DU ROLE DU TRANSPORT MEMBRANAIRE, DE LA POLYGLUTAMATION DU METHOTREXATE DANS LES INTESTINS ET LA TUMEUR D'EHRLICH IN VIVO COMME FACTEURS DE LA SENSIBILITE ET SELECTIVITE DE LA DROGUEFRY DW; ANDERSON LA; BORST M et al.1983; CANCER RESEARCH; ISSN 0008-5472; USA; DA. 1983; VOL. 43; NO 3; PP. 1087-1092; ABS. ENG; BIBL. 39 REF.; GRAPHArticle

TRANSPORT, BINDING, AND POLYGLUTAMATION OF METHOTREXATE IN FRESHLY ISOLATED RAT HEPATOCYTESGEWIRTZ DA; WHITE JC; RANDOLPH JK et al.1980; CANCER RES.; USA; DA. 1980; VOL. 40; NO 3; PP. 573-578; BIBL. 37 REF.Article

FORMATION OF METHOTREXATE POLYGLUTAMATES IN RAT HEPATOCYTESGEWIRTZ DA; WHITE JC; RANDOLPH JK et al.1979; CANCER RES.; USA; DA. 1979; VOL. 39; NO 8; PP. 2914-2918; BIBL. 37 REF.Article

THE EFFECT OF MICROTUBULAR INHIBITORS ON TRANSPORT OF ALPHA -AMINOISOBUTYRIC ACID. INHIBITION OF UPHILL TRANSPORT WITHOUT CHANGES IN TRANSMEMBRANE GRADIENTS OF NA⁺, K⁺, OR H⁺.GOLDMAN ID; FYFE MJ; BOWEN D et al.1977; BIOCHIM. BIOPHYS. ACTA; PAYS-BAS; DA. 1977; VOL. 467; NO 2; PP. 185-191; BIBL. 20 REF.Article

RELATIONSHIP BETWEEN MEMBRANE TRANSPORT OF METHOTREXATE AND ENDOGENOUS CYCLIC ADENOSINE 3':5'-MONOPHOSPHATE IN THE EHRLICH ASCITES TUMORCOURTLAND WHITE J; CARCHMAN RA; FRY DW et al.1980; CANCER RES.; USA; DA. 1980; VOL. 40; NO 7; PP. 2400-2404; BIBL. 22 REF.Article